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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN966418 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Insulin Receptor Substrate 1 (IRS1) antibody
- Antibody type
- Polyclonal
- Antigen
- The antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 636 (P-M-SP-P-K).
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100 μg
- Concentration
- 100ug/100ul.
- Storage
- -20°C
Submitted references Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation.
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
Insights into insulin resistance and type 2 diabetes from knockout mouse models.
Tzatsos A, Kandror KV
Molecular and cellular biology 2006 Jan;26(1):63-76
Molecular and cellular biology 2006 Jan;26(1):63-76
A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB
Proceedings of the National Academy of Sciences of the United States of America 2001 Apr 10;98(8):4640-5
Proceedings of the National Academy of Sciences of the United States of America 2001 Apr 10;98(8):4640-5
Insights into insulin resistance and type 2 diabetes from knockout mouse models.
Kadowaki T
The Journal of clinical investigation 2000 Aug;106(4):459-65
The Journal of clinical investigation 2000 Aug;106(4):459-65
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