orb18057

antibody from Biorbyt

Targeting: RTN4 ASY, KIAA0886, NOGO, NSP-CL

Immunohistochemistry

Antibody data

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Validation data

Product number: orb18057 - Provider product page
Provider: Biorbyt
Proper citation: Biorbyt Cat#orb18057, RRID:AB_10756477
Product name: RTN4 antibody
Antibody type: Polyclonal
Description: Rabbit Polyclonal to RTN4. Human neurite outgrowth inhibitor (NOGO) cDNAs encodes 3 splice variants: NOGOA, NOGOB and NOGOC. The longest cDNA, designated NOGOA, has an open reading frame of 1192 amino acids. It is a potent inhibitor of neurite growth and an IN-1 antigen produced by oligodendrocytes, and may allow the generation of new reagents to enhance CNS regeneration and plasticity. Nogo-A, a member of the Reticulon family, is expressed by oligodendrocytes and associates primarily with the endoplasmic reticulum. The acidic amino terminus of Nogo-A is detected at the cytosolic face of cellular membranes and may contribute to inhibition of axon regeneration at sites of oligodendrocyte injury. A multivalent form of the N terminus of Nogo-A affects the morphology of both neurons and other cell types.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Vial size: 100 μg
Concentration: Lyophilized Powder
Storage: Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

RTN4 protein structure - orb18057 shown in red.