Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NBP2-33182 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal VCAM-1/CD106 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references A Role for Human Skin Mast Cells in Dengue Virus Infection and Systemic Spread.
Troupin A, Shirley D, Londono-Renteria B, Watson AM, McHale C, Hall A, Hartstone-Rose A, Klimstra WB, Gomez G, Colpitts TM
Journal of immunology (Baltimore, Md. : 1950) 2016 Dec 1;197(11):4382-4391
Journal of immunology (Baltimore, Md. : 1950) 2016 Dec 1;197(11):4382-4391
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: VCAM-1/CD106 Antibody (1.4C3) - Azide and BSA Free [NBP2-33182] - Analysis using HDMVEC cell lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: VCAM-1/CD106 Antibody (1.4C3) - Azide and BSA Free [NBP2-33182] - Analysis using In-cell ELISA with HDMVEC cells.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody (1.4C3) - Azide and BSA Free [NBP2-33182] - Formalin-fixed, paraffin-embedded human tonsil stained with VCAM1 / CD106 antibody at 1:100 using peroxidase-conjugate and DAB chromogen. Note membrane staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody (1.4C3) - Azide and BSA Free [NBP2-33182] - Formalin-fixed, paraffin-embedded human tonsil stained with VCAM1 / CD106 antibody at 1:100 using peroxidase-conjugate and DAB chromogen. Note membrane staining.