ABIN350148

antibody from antibodies-online

Targeting: CACNA1S CACNL1A3, Cav1.1, HOKPP, hypoPP, MHS5

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN350148

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN350148, RRID:AB_10782499

Product name

anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S) (N-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide from n-terminal of human CACNA1S (Cav1.1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Description

Whole serum

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

N-Term

Vial size

100 μL

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

Voltage sensor charge loss accounts for most cases of hypokalemic periodic paralysis.

Matthews E, Labrum R, Sweeney MG, Sud R, Haworth A, Chinnery PF, Meola G, Schorge S, Kullmann DM, Davis MB, Hanna MG
Neurology 2009 May 5;72(18):1544-7

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Hypokalaemic periodic paralysis due to the CACNA1S R1239H mutation in a large African family.

Houinato D, Laleye A, Adjien C, Adjagba M, Sternberg D, Hilbert P, Vallat JM, Darboux RB, Funalot B, Avode DG
Neuromuscular disorders : NMD 2007 May;17(5):419-22

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Cloning of the human skeletal muscle alpha 1 subunit of the dihydropyridine-sensitive L-type calcium channel (CACNL1A3).

Hogan K, Powers PA, Gregg RG
Genomics 1994 Dec;24(3):608-9

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A calcium channel mutation causing hypokalemic periodic paralysis.

Jurkat-Rott K, Lehmann-Horn F, Elbaz A, Heine R, Gregg RG, Hogan K, Powers PA, Lapie P, Vale-Santos JE, Weissenbach J
Human molecular genetics 1994 Aug;3(8):1415-9