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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- 11-4025 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-S1PR1 Antibody
- Antibody type
- Polyclonal
- Description
- Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 plays an important role in cell migration reorganizing the actin cytoskeleton and by the formation of lamellipodia in response to the activity of sphingosine kinase SPHK1. Diseases associated with S1PR1 include follicular thyroid carcinoma and multiple sclerosis. It is mainly expressed on endothelial cells, vascular smooth muscle cells (low), fibroblasts, melanocytes and cells of epithelioid origin.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant S1PR1
protein (amino acids 1-320) was use
d as the immunogen for this antibod
y.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
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- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of S1PR1 . Anti-S1PR1 antibody (11-4025) was used at 4 µg/ml on A375 lysate.
