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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Product number
- GTX113039 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX113039, RRID:AB_1949738
- Product name
- Beclin 1 antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant fragment corresponding to a region within amino acids 233 and 450 of Beclin 1 (Uniprot ID#Q14457)
- Reactivity
- Bovine, Chicken/Avian, Porcine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 25 µl, 100 µl
- Concentration
- 1 mg/ml
- Storage
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Submitted references A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells.
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition.
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner.
Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine.
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells.
Ovothiol isolated from sea urchin oocytes induces autophagy in the Hep-G2 cell line.
Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy.
Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.
Wei RJ, Lin SS, Wu WR, Chen LR, Li CF, Chen HD, Chou CT, Chen YC, Liang SS, Chien ST, Shiue YL
Toxicology and applied pharmacology 2016 Nov 15;311:88-98
Toxicology and applied pharmacology 2016 Nov 15;311:88-98
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition.
Cordani M, Oppici E, Dando I, Butturini E, Dalla Pozza E, Nadal-Serrano M, Oliver J, Roca P, Mariotto S, Cellini B, Blandino G, Palmieri M, Di Agostino S, Donadelli M
Molecular oncology 2016 Aug;10(7):1008-29
Molecular oncology 2016 Aug;10(7):1008-29
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner.
Fiorini C, Cordani M, Gotte G, Picone D, Donadelli M
Biochimica et biophysica acta 2015 Mar;1853(3):549-60
Biochimica et biophysica acta 2015 Mar;1853(3):549-60
Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine.
Fiorini C, Cordani M, Padroni C, Blandino G, Di Agostino S, Donadelli M
Biochimica et biophysica acta 2015 Jan;1853(1):89-100
Biochimica et biophysica acta 2015 Jan;1853(1):89-100
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells.
Fiorini C, Gotte G, Donnarumma F, Picone D, Donadelli M
Biochimica et biophysica acta 2014 May;1843(5):976-84
Biochimica et biophysica acta 2014 May;1843(5):976-84
Ovothiol isolated from sea urchin oocytes induces autophagy in the Hep-G2 cell line.
Russo GL, Russo M, Castellano I, Napolitano A, Palumbo A
Marine drugs 2014 Jul 7;12(7):4069-85
Marine drugs 2014 Jul 7;12(7):4069-85
Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy.
Lee YR, Wu WC, Ji WT, Chen JY, Cheng YP, Chiang MK, Chen HR
Journal of biomedical science 2012 Jan 27;19:9
Journal of biomedical science 2012 Jan 27;19:9
Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.
Su WC, Chao TC, Huang YL, Weng SC, Jeng KS, Lai MM
Journal of virology 2011 Oct;85(20):10561-71
Journal of virology 2011 Oct;85(20):10561-71
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