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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN968675 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Exportin 1, CRM1 Homolog (Yeast) (XPO1) (AA 2-122) antibody
- Antibody type
- Monoclonal
- Antigen
- Human hCRM1
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 2-122
- Isotype
- IgG
- Antibody clone number
- 17
- Vial size
- 150 μg
- Concentration
- 250 μg/ml
- Storage
- -20°C
Submitted references Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase.
The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway.
Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export.
CRM1-mediated recycling of snurportin 1 to the cytoplasm.
Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis.
CRM1 is an export receptor for leucine-rich nuclear export signals.
Kamura T, Hara T, Matsumoto M, Ishida N, Okumura F, Hatakeyama S, Yoshida M, Nakayama K, Nakayama KI
Nature cell biology 2004 Dec;6(12):1229-35
Nature cell biology 2004 Dec;6(12):1229-35
The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway.
Massenet S, Pellizzoni L, Paushkin S, Mattaj IW, Dreyfuss G
Molecular and cellular biology 2002 Sep;22(18):6533-41
Molecular and cellular biology 2002 Sep;22(18):6533-41
Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export.
Ishida N, Hara T, Kamura T, Yoshida M, Nakayama K, Nakayama KI
The Journal of biological chemistry 2002 Apr 26;277(17):14355-8
The Journal of biological chemistry 2002 Apr 26;277(17):14355-8
CRM1-mediated recycling of snurportin 1 to the cytoplasm.
Paraskeva E, Izaurralde E, Bischoff FR, Huber J, Kutay U, Hartmann E, Lührmann R, Görlich D
The Journal of cell biology 1999 Apr 19;145(2):255-64
The Journal of cell biology 1999 Apr 19;145(2):255-64
Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis.
Boer J, Bonten-Surtel J, Grosveld G
Molecular and cellular biology 1998 Mar;18(3):1236-47
Molecular and cellular biology 1998 Mar;18(3):1236-47
CRM1 is an export receptor for leucine-rich nuclear export signals.
Fornerod M, Ohno M, Yoshida M, Mattaj IW
Cell 1997 Sep 19;90(6):1051-60
Cell 1997 Sep 19;90(6):1051-60
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