H017T02R03

antibody from Invitrogen Antibodies
Targeting: IL7R CD127, IL7RA
Provider product page for H017T02R03

Antibody data

Product number
H017T02R03 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD127 Monoclonal Antibody (eBioRDR5), NovaFluor™ Red 700, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The eBioRDR5 monoclonal antibody reacts with human CD127 (Interleukin-7 Receptor alpha). CD127 complexes with CD132, also known as the common gamma chain (gamma c), to form the multi-functional IL-7 receptor (IL-7R). CD127 is a type I glycoprotein with a molecular weight of 75-80 kDa and is expressed by immature B cells through the early pre-B stage, by thymocytes during several stages of their development, and on most mature T cells, with transient down-regulation upon activation. Binding of IL-7 results in signal transduction which occurs through several tyrosine kinase pathways including the Jak/STAT pathway. IL-7 is indispensible for the development of lymphocytes, and the control of homeostatic proliferation of T-cells in the periphery. In addition, IL-7R signaling is know to be involved in the regulation of T cell receptor (TCR) locus rearrangement in gamma delta T cells.
Conjugate
Near infrared dye
Antibody clone number
eBioRDR5
Concentration
5 µL/Test
IL7R protein structure - H017T02R03 shown in red.