Antibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN2841777 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 19-51), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 19-51, N-Term
- Antibody clone number
- RB1455-1456
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Growth-suppressing function of glypican-3 (GPC3) via insulin like growth factor II (IGF-II) signaling pathway in ovarian clear cell carcinoma cells.
Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node metastasis in human colorectal cancer.
PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells.
Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells.
The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane.
Sakurai M, Shibata K, Umezu T, Kajiyama H, Yamamoto E, Ino K, Nawa A, Kikkawa F
Gynecologic oncology 2010 Nov;119(2):332-6
Gynecologic oncology 2010 Nov;119(2):332-6
Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node metastasis in human colorectal cancer.
Zhang C, Hao L, Wang L, Xiao Y, Ge H, Zhu Z, Luo Y, Zhang Y, Zhang Y
BMC cancer 2010 May 7;10:184
BMC cancer 2010 May 7;10:184
PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells.
Zhao H, Dupont J, Yakar S, Karas M, LeRoith D
Oncogene 2004 Jan 22;23(3):786-94
Oncogene 2004 Jan 22;23(3):786-94
Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells.
Lu Y, Zi X, Zhao Y, Pollak M
Biochemical and biophysical research communications 2004 Jan 16;313(3):709-15
Biochemical and biophysical research communications 2004 Jan 16;313(3):709-15
The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane.
Song RX, Barnes CJ, Zhang Z, Bao Y, Kumar R, Santen RJ
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 17;101(7):2076-81
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 17;101(7):2076-81
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC