Antibody data

Product number
46-9855-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
c-MAF Monoclonal Antibody (sym0F1), PerCP-eFluor™ 710, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The sym0F1 monoclonal antibody reacts with human and mouse c-Maf, a 42 kDa basic leucine zipper transcription factor shown to be involved in the neural, ocular and hematopoietic systems. In hematopoietic cells, it was first shown to be crucial for IL-4 expression in Th2 and was the first transcription factor believed to be Th subset-specific. More recent evidence shows that specific phospho-tyrosine residues lead to upregulation of IL-4. c-Maf has also been shown to be important to differentiation and function in both Th17 and Tfh cells. It drives expression of IL-21 in both cell types, while promoting expression of IL-23R in Th17 and CXCR5 in Tfh as well.
Antibody clone number
sym0F1
Concentration
5 µL/Test
MAF protein structure - 46-9855-41 shown in red.