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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Flow cytometry [2]
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- Product number
- FAB1726A - Provider product page
- Provider
- R&D Systems
- Product name
- Human/Mouse Jagged 1/Jagged 2 APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Stains human Jagged 1 and Jagged 2 transfectants but not the parental cell line by flow cytometry. Detects endogenous human and mouse Jagged 1 and Jagged 2 by flow cytometry.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Red dye
- Antigen sequence
Q9Y219- Isotype
- IgG
- Antibody clone number
- 241002
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence.
NOTCH1 mediates a switch between two distinct secretomes during senescence.
Parry AJ, Hoare M, Bihary D, Hänsel-Hertsch R, Smith S, Tomimatsu K, Mannion E, Smith A, D'Santos P, Russell IA, Balasubramanian S, Kimura H, Samarajiwa SA, Narita M
Nature communications 2018 May 9;9(1):1840
Nature communications 2018 May 9;9(1):1840
NOTCH1 mediates a switch between two distinct secretomes during senescence.
Hoare M, Ito Y, Kang TW, Weekes MP, Matheson NJ, Patten DA, Shetty S, Parry AJ, Menon S, Salama R, Antrobus R, Tomimatsu K, Howat W, Lehner PJ, Zender L, Narita M
Nature cell biology 2016 Sep;18(9):979-92
Nature cell biology 2016 Sep;18(9):979-92
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Jagged 1/Jagged 2 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human/Mouse Jagged 1/Jagged 2 APC-conjugated Monoclonal Antibody (Catalog # FAB1726A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Jagged 1/Jagged 2 in D3 Mouse Cell Line by Flow Cytometry. D3 mouse embryonic stem cell line was stained with Mouse Anti-Human/Mouse Jagged 1/Jagged 2 APC-conjugated Monoclonal Antibody (Catalog # FAB1726A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.
