ABIN1003223

antibody from antibodies-online

Targeting: SOCS1 Cish1, JAB, SOCS-1, SSI-1, TIP3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN1003223

Provider

antibodies-online

Product name

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

SOCS1 antibody was raised against an 15 amino acid peptide from near the carboxy terminus of human SOCS1.

Description

Affinity chromatography purified via peptide column.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.

References

Submitted references

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation.

Mansell A, Smith R, Doyle SL, Gray P, Fenner JE, Crack PJ, Nicholson SE, Hilton DJ, O'Neill LA, Hertzog PJ
Nature immunology 2006 Feb;7(2):148-55

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Controlling cytokine signaling by constitutive inhibitors.

Rakesh K, Agrawal DK
Biochemical pharmacology 2005 Sep 1;70(5):649-57

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The SOCS box: a tale of destruction and degradation.

Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ
Trends in biochemical sciences 2002 May;27(5):235-41

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Cytokine signaling in 2002: new surprises in the Jak/Stat pathway.

O'Shea JJ, Gadina M, Schreiber RD
Cell 2002 Apr;109 Suppl:S121-31