MA5-14416
antibody from Invitrogen Antibodies
Targeting: RAD51
BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA
Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- MA5-14416 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-RAD51 Monoclonal Antibody (51RAD01 (3C10)), Biotin
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- MA5-14419 targets RAD51 in IHC (P), IP, ICC/IF and WB applications and shows reactivity with Human, mouse, and Rat samples. The MA5-14419 immunogen is recombinant Rad51 protein.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- 51RAD01 (3C10)
- Vial size
- 500 µL
- Concentration
- 0.2 mg/ml
- Storage
- 4° C
Submitted references Rad51 expression is a useful predictive factor for the efficacy of neoadjuvant chemoradiotherapy in squamous cell carcinoma of the esophagus.
Gene expression profiling reveals activation of the FA/BRCA pathway in advanced squamous cervical cancer with intrinsic resistance and therapy failure.
A single cohesin complex performs mitotic and meiotic functions in the protist tetrahymena.
Human papillomavirus in oral atrophic lichen planus lesions.
Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1.
The Tetrahymena meiotic chromosome bouquet is organized by centromeres and promotes interhomolog recombination.
The recombinases Rad51 and Dmc1 play distinct roles in DNA break repair and recombination partner choice in the meiosis of Tetrahymena.
The role of meiotic cohesin REC8 in chromosome segregation in gamma irradiation-induced endopolyploid tumour cells.
p63 and p73 transcriptionally regulate genes involved in DNA repair.
DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena.
Selenium protection from DNA damage involves a Ref1/p53/Brca1 protein complex.
Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombe.
Interaction of radiation- and bleomycin-induced lesions and influence of glutathione level on the interaction.
Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva).
Organization and pairing of meiotic chromosomes in the ciliate Tetrahymena thermophila.
Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response.
Endopolyploid cells produced after severe genotoxic damage have the potential to repair DNA double strand breaks.
Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals.
Nakanoko T, Saeki H, Morita M, Nakashima Y, Ando K, Oki E, Ohga T, Kakeji Y, Toh Y, Maehara Y
Annals of surgical oncology 2014 Feb;21(2):597-604
Annals of surgical oncology 2014 Feb;21(2):597-604
Gene expression profiling reveals activation of the FA/BRCA pathway in advanced squamous cervical cancer with intrinsic resistance and therapy failure.
Balacescu O, Balacescu L, Tudoran O, Todor N, Rus M, Buiga R, Susman S, Fetica B, Pop L, Maja L, Visan S, Ordeanu C, Berindan-Neagoe I, Nagy V
BMC cancer 2014 Apr 8;14:246
BMC cancer 2014 Apr 8;14:246
A single cohesin complex performs mitotic and meiotic functions in the protist tetrahymena.
Howard-Till RA, Lukaszewicz A, Novatchkova M, Loidl J
PLoS genetics 2013 Mar;9(3):e1003418
PLoS genetics 2013 Mar;9(3):e1003418
Human papillomavirus in oral atrophic lichen planus lesions.
Mattila R, Rautava J, Syrjänen S
Oral oncology 2012 Oct;48(10):980-984
Oral oncology 2012 Oct;48(10):980-984
Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1.
Hsu JK, Lin T, Tsai RY
The Journal of cell biology 2012 May 28;197(5):613-24
The Journal of cell biology 2012 May 28;197(5):613-24
The Tetrahymena meiotic chromosome bouquet is organized by centromeres and promotes interhomolog recombination.
Loidl J, Lukaszewicz A, Howard-Till RA, Koestler T
Journal of cell science 2012 Dec 1;125(Pt 23):5873-80
Journal of cell science 2012 Dec 1;125(Pt 23):5873-80
The recombinases Rad51 and Dmc1 play distinct roles in DNA break repair and recombination partner choice in the meiosis of Tetrahymena.
Howard-Till RA, Lukaszewicz A, Loidl J
PLoS genetics 2011 Mar;7(3):e1001359
PLoS genetics 2011 Mar;7(3):e1001359
The role of meiotic cohesin REC8 in chromosome segregation in gamma irradiation-induced endopolyploid tumour cells.
Erenpreisa J, Cragg MS, Salmina K, Hausmann M, Scherthan H
Experimental cell research 2009 Sep 10;315(15):2593-603
Experimental cell research 2009 Sep 10;315(15):2593-603
p63 and p73 transcriptionally regulate genes involved in DNA repair.
Lin YL, Sengupta S, Gurdziel K, Bell GW, Jacks T, Flores ER
PLoS genetics 2009 Oct;5(10):e1000680
PLoS genetics 2009 Oct;5(10):e1000680
DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena.
Mochizuki K, Novatchkova M, Loidl J
Journal of cell science 2008 Jul 1;121(Pt 13):2148-58
Journal of cell science 2008 Jul 1;121(Pt 13):2148-58
Selenium protection from DNA damage involves a Ref1/p53/Brca1 protein complex.
Fischer JL, Lancia JK, Mathur A, Smith ML
Anticancer research 2006 Mar-Apr;26(2A):899-904
Anticancer research 2006 Mar-Apr;26(2A):899-904
Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombe.
Lorenz A, Estreicher A, Kohli J, Loidl J
Chromosoma 2006 Aug;115(4):330-40
Chromosoma 2006 Aug;115(4):330-40
Interaction of radiation- and bleomycin-induced lesions and influence of glutathione level on the interaction.
Dutta A, Chakraborty A, Saha A, Ray S, Chatterjee A
Mutagenesis 2005 Sep;20(5):329-35
Mutagenesis 2005 Sep;20(5):329-35
Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva).
Chinnaiyan P, Huang S, Vallabhaneni G, Armstrong E, Varambally S, Tomlins SA, Chinnaiyan AM, Harari PM
Cancer research 2005 Apr 15;65(8):3328-35
Cancer research 2005 Apr 15;65(8):3328-35
Organization and pairing of meiotic chromosomes in the ciliate Tetrahymena thermophila.
Loidl J, Scherthan H
Journal of cell science 2004 Nov 15;117(Pt 24):5791-801
Journal of cell science 2004 Nov 15;117(Pt 24):5791-801
Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response.
Wilkinson DE, Weller SK
Journal of virology 2004 May;78(9):4783-96
Journal of virology 2004 May;78(9):4783-96
Endopolyploid cells produced after severe genotoxic damage have the potential to repair DNA double strand breaks.
Ivanov A, Cragg MS, Erenpreisa J, Emzinsh D, Lukman H, Illidge TM
Journal of cell science 2003 Oct 15;116(Pt 20):4095-106
Journal of cell science 2003 Oct 15;116(Pt 20):4095-106
Analysis of murine Brca2 reveals conservation of protein-protein interactions but differences in nuclear localization signals.
Sarkisian CJ, Master SR, Huber LJ, Ha SI, Chodosh LA
The Journal of biological chemistry 2001 Oct 5;276(40):37640-8
The Journal of biological chemistry 2001 Oct 5;276(40):37640-8
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human testis stained with Rad 51 antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of germ cells.
- Conjugate
- Biotin
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of RAD51 using RAD51 Monoclonal Antibody (Product # MA5-14416) on Native Human LS174T Cells.
- Conjugate
- Biotin