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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB683P - Provider product page
- Provider
- R&D Systems
- Product name
- Human RANK/TNFRSF11A PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human RANK/TNFRSF11A in ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFas, rhGITR, rhHVEM, rhLymphotoxin beta R, rhNGF R, rhOPG, rhTAJ, rhTNF RI, rhTNF RII, or recombinant mouse (rm) OX40, and rmRANK is observed.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Q9Y6Q6- Isotype
- IgG
- Antibody clone number
- 80704
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Human polymorphonuclear neutrophils express RANK and are activated by its ligand, RANKL.
Riegel A, Maurer T, Prior B, Stegmaier S, Heppert V, Wagner C, Hänsch GM
European journal of immunology 2012 Apr;42(4):975-81
European journal of immunology 2012 Apr;42(4):975-81
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of RANK/TNFRSF11A in A431 Human Cell Line by Flow Cytometry. A431 human epithelial carcinoma cell line was stained with Mouse Anti-Human RANK/TNFRSF11A PE-conjugated Monoclonal Antibody (Catalog # FAB683P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
