ABIN363148

antibody from antibodies-online

Targeting: NFKBIB IKBB, TRIP9

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN363148

Provider

antibodies-online

Product name

anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) (pSer23) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer23 (L-G-S (p) -L-G) derived from Human IkB-b. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer23

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1.

Shirane M, Hatakeyama S, Hattori K, Nakayama K, Nakayama K
The Journal of biological chemistry 1999 Oct 1;274(40):28169-74

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation.

DiDonato J, Mercurio F, Rosette C, Wu-Li J, Suyang H, Ghosh S, Karin M
Molecular and cellular biology 1996 Apr;16(4):1295-304