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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 331814 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#331814, RRID:AB_2565235
- Product name
- PerCP/Cy5.5 anti-human CD319 (CRACC)
- Antibody type
- Monoclonal
- Antigen
- CRACC-Human IgG1 fusion protein
- Description
- CD319 is a single-pass type l transmembrane glycoprotein, expressed on NK cells, subsets of mature dendritic cells, activated B cells, and cytotoxic lymphocytes, but not in promyelocytic, B or T cell lines. Expression is highest in the spleen, lymph nodes, and peripheral blood leukocytes, and lowest in bone marrow. Additionally, it is expressed in the small intestine, stomach, appendix, lung, and trachea. CD319 is tyrosine phosphorylated in activated NK cells and is associated with 19 and 39 kD proteins. CD319 has homology with the CD2 family of receptors within the Ig superfamily. Some of the CD2 members stimulate cytotoxicity through the CD319 associated protein.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 162.1
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood lymphocytes were stained with CD3 FITC and CD319 (clone 162.1) PerCP/Cy5.5 (top) or mouse IgG2b, κ PerCP/Cy5.5 isotype control (bottom).
