Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB331F-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CXCR2/IL-8RB Fluorescein-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human CXCR2/IL-8 RB transfected NS0 cells but not the parental cell line. It does not cross-react with CXCR1 (IL-8 RA).
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAB25880
- Isotype
- IgG
- Antibody clone number
- 48311
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals.
CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis.
HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells.
Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals.
Hazeldine J, Harris P, Chapple IL, Grant M, Greenwood H, Livesey A, Sapey E, Lord JM
Aging cell 2014 Aug;13(4):690-8
Aging cell 2014 Aug;13(4):690-8
CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis.
Yang G, Rosen DG, Liu G, Yang F, Guo X, Xiao X, Xue F, Mercado-Uribe I, Huang J, Lin SH, Mills GB, Liu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Aug 1;16(15):3875-86
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Aug 1;16(15):3875-86
HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells.
Maxwell PJ, Gallagher R, Seaton A, Wilson C, Scullin P, Pettigrew J, Stratford IJ, Williams KJ, Johnston PG, Waugh DJ
Oncogene 2007 Nov 15;26(52):7333-45
Oncogene 2007 Nov 15;26(52):7333-45
Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W
European journal of immunology 2005 Sep;35(9):2573-82
European journal of immunology 2005 Sep;35(9):2573-82
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CXCR2/IL-8 RB in Human Peripheral Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB331F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.