NBP2-33080UV

antibody from Novus Biologicals

Targeting: CR1 CD35, KN

ELISA (Data presented on provider website)

Antibody Data

Product number

NBP2-33080UV

Provider

Novus Biologicals

Product name

Mouse Monoclonal CD35 Antibody

Antibody type

Monoclonal

Description

Protein G purified. Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.

Reactivity

Human, Simian

Host

Mouse

Conjugate

Blue dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.