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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [10]
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- Product number
- BAF246 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal LAP (TGF-beta 1) Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human LAP TGF-beta 1 in Western blots. In this format, less than 1% cross-reactivity with mature recombinant human (rh) TGF-beta 1, porcine TGF-beta 2, rhTGF-beta 3, and recombinant amphibian TGF-beta 5 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells.
Overexpression of TGF-ß 1 gene induces cell surface localized glucose-regulated protein 78-associated latency-associated peptide/TGF-ß.
Involvement of regulatory T cells in the immunosuppression characteristic of patients with paracoccidioidomycosis.
Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens.
Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg.
T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.
Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White)F1 mice suppress in vitro production of antibodies to DNA.
Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White)F1 mice suppress in vitro production of antibodies to DNA.
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Huygens C, Liénart S, Dedobbeleer O, Stockis J, Gauthy E, Coulie PG, Lucas S
The Journal of biological chemistry 2015 Aug 14;290(33):20105-16
The Journal of biological chemistry 2015 Aug 14;290(33):20105-16
Overexpression of TGF-ß 1 gene induces cell surface localized glucose-regulated protein 78-associated latency-associated peptide/TGF-ß.
Oida T, Weiner HL
Journal of immunology (Baltimore, Md. : 1950) 2010 Sep 15;185(6):3529-35
Journal of immunology (Baltimore, Md. : 1950) 2010 Sep 15;185(6):3529-35
Involvement of regulatory T cells in the immunosuppression characteristic of patients with paracoccidioidomycosis.
Ferreira MC, de Oliveira RT, da Silva RM, Blotta MH, Mamoni RL
Infection and immunity 2010 Oct;78(10):4392-401
Infection and immunity 2010 Oct;78(10):4392-401
Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens.
Burton OT, Gibbs S, Miller N, Jones FM, Wen L, Dunne DW, Cooke A, Zaccone P
European journal of immunology 2010 Aug;40(8):2221-9
European journal of immunology 2010 Aug;40(8):2221-9
Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg.
Stockis J, Colau D, Coulie PG, Lucas S
European journal of immunology 2009 Dec;39(12):3315-22
European journal of immunology 2009 Dec;39(12):3315-22
T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.
Pesu M, Watford WT, Wei L, Xu L, Fuss I, Strober W, Andersson J, Shevach EM, Quezado M, Bouladoux N, Roebroek A, Belkaid Y, Creemers J, O'Shea JJ
Nature 2008 Sep 11;455(7210):246-50
Nature 2008 Sep 11;455(7210):246-50
Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White)F1 mice suppress in vitro production of antibodies to DNA.
La Cava A, Ebling FM, Hahn BH
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 1;173(5):3542-8
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 1;173(5):3542-8
Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White)F1 mice suppress in vitro production of antibodies to DNA.
La Cava A, Ebling FM, Hahn BH
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 1;173(5):3542-8
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 1;173(5):3542-8
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Torrealba JR, Katayama M, Fechner JH Jr, Jankowska-Gan E, Kusaka S, Xu Q, Schultz JM, Oberley TD, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5753-64
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5753-64
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Torrealba JR, Katayama M, Fechner JH Jr, Jankowska-Gan E, Kusaka S, Xu Q, Schultz JM, Oberley TD, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5753-64
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5753-64
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