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Western blot
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [53]
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- Validations
- Blocking/Neutralizing [1]
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- Product number
- AB-100-NA - Provider product page
- Provider
- R&D Systems
- Product name
- TGF-beta Pan Specific Antibody
- Antibody type
- Polyclonal
- Description
- Protein A or G purified. Detects TGF-beta 1, TGF-beta 1.2, TGF-beta 2, TGF-beta 3, and TGF-beta 5 in direct ELISAs and Western blots.
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 1 mg
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references DNA methylation affects metastasis of renal cancer and is associated with TGF-β/RUNX3 inhibition.
Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion.
Cardiac macrophages promote diastolic dysfunction.
The IL-2/Anti-IL-2 Complex Attenuates Cardiac Ischaemia-Reperfusion Injury Through Expansion of Regulatory T Cells.
Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation.
TGF-β contamination of purified recombinant GDF15.
ST2/IL-33-Dependent Microglial Response Limits Acute Ischemic Brain Injury.
MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrotic properties.
Endoplasmic Reticulum Oxidative Stress Triggers Tgf-Beta-Dependent Muscle Dysfunction by Accelerating Ascorbic Acid Turnover.
Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice.
TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.
Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells.
Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts.
Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.
Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment.
CD4(+)Foxp3(+) Tregs protect against innate immune cell-mediated fulminant hepatitis in mice.
Emdogain-regulated gene expression in palatal fibroblasts requires TGF-βRI kinase signaling.
Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-β and induce Tregs development via TGF-β.
Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF.
Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor β (TGFβ)-, epidermal growth factor (EGF)-, and nuclear factor κB (NFκB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion.
Platelets provoke distinct dynamics of immune responses by differentially regulating CD4+ T-cell proliferation.
IL-2/anti-IL-2 complex attenuates renal ischemia-reperfusion injury through expansion of regulatory T cells.
Toll-like receptor 2 (TLR2), transforming growth factor-β, hyaluronan (HA), and receptor for HA-mediated motility (RHAMM) are required for surfactant protein A-stimulated macrophage chemotaxis.
Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis.
Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade.
IL-33 induces IL-9 production in human CD4+ T cells and basophils.
Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.
Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche.
The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Interferon-gamma and the interferon-inducible chemokine CXCL10 protect against aneurysm formation and rupture.
Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling.
Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
Local administration of interleukin-11 ameliorates intestinal radiation injury in rats.
Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease.
Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.
Increase in transforming growth factor-beta in the brain during infection is related to fever, not depression of spontaneous motor activity.
Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?
Uptake of host cell transforming growth factor-beta by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion.
Uptake of host cell transforming growth factor-beta by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion.
Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.
Thrombospondin plays a vital role in the immune privilege of the eye.
Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice.
Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity.
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
Effect of weightbearing on bone formation during distraction osteogenesis.
Effect of weightbearing on bone formation during distraction osteogenesis.
Connective tissue growth factor and its correlation to other growth factors in experimental granulation tissue.
Estrogen inhibition of PTH-stimulated osteoclast formation and attachment in vitro: involvement of both PKA and PKC.
Zheng J, Mei Y, Xiang P, Zhai G, Zhao N, Xu C, Liu M, Pan Z, Tang K, Jia D
Cancer cell international 2018;18:56
Cancer cell international 2018;18:56
Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion.
Ibrahim M, Scozzi D, Toth KA, Ponti D, Kreisel D, Menna C, De Falco E, D'Andrilli A, Rendina EA, Calogero A, Krupnick AS, Gelman AE
Journal of immunology (Baltimore, Md. : 1950) 2018 Jan 15;200(2):847-856
Journal of immunology (Baltimore, Md. : 1950) 2018 Jan 15;200(2):847-856
Cardiac macrophages promote diastolic dysfunction.
Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M
The Journal of experimental medicine 2018 Feb 5;215(2):423-440
The Journal of experimental medicine 2018 Feb 5;215(2):423-440
The IL-2/Anti-IL-2 Complex Attenuates Cardiac Ischaemia-Reperfusion Injury Through Expansion of Regulatory T Cells.
Xiao J, Yu K, Li M, Xiong C, Wei Y, Zeng Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(5):1810-1827
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(5):1810-1827
Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation.
Selvamurugan N, He Z, Rifkin D, Dabovic B, Partridge NC
Stem cells international 2017;2017:2450327
Stem cells international 2017;2017:2450327
TGF-β contamination of purified recombinant GDF15.
Olsen OE, Skjærvik A, Størdal BF, Sundan A, Holien T
PloS one 2017;12(11):e0187349
PloS one 2017;12(11):e0187349
ST2/IL-33-Dependent Microglial Response Limits Acute Ischemic Brain Injury.
Yang Y, Liu H, Zhang H, Ye Q, Wang J, Yang B, Mao L, Zhu W, Leak RK, Xiao B, Lu B, Chen J, Hu X
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 May 3;37(18):4692-4704
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 May 3;37(18):4692-4704
MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrotic properties.
Poveda J, Sanz AB, Fernandez-Fernandez B, Carrasco S, Ruiz-Ortega M, Cannata-Ortiz P, Ortiz A, Sanchez-Niño MD
Journal of cellular and molecular medicine 2017 Jan;21(1):154-164
Journal of cellular and molecular medicine 2017 Jan;21(1):154-164
Endoplasmic Reticulum Oxidative Stress Triggers Tgf-Beta-Dependent Muscle Dysfunction by Accelerating Ascorbic Acid Turnover.
Pozzer D, Favellato M, Bolis M, Invernizzi RW, Solagna F, Blaauw B, Zito E
Scientific reports 2017 Jan 20;7:40993
Scientific reports 2017 Jan 20;7:40993
Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice.
Rouf R, MacFarlane EG, Takimoto E, Chaudhary R, Nagpal V, Rainer PP, Bindman JG, Gerber EE, Bedja D, Schiefer C, Miller KL, Zhu G, Myers L, Amat-Alarcon N, Lee DI, Koitabashi N, Judge DP, Kass DA, Dietz HC
JCI insight 2017 Aug 3;2(15)
JCI insight 2017 Aug 3;2(15)
TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.
Chen X, Rateri DL, Howatt DA, Balakrishnan A, Moorleghen JJ, Cassis LA, Daugherty A
PloS one 2016;11(4):e0153811
PloS one 2016;11(4):e0153811
Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells.
Veltmann M, Hollborn M, Reichenbach A, Wiedemann P, Kohen L, Bringmann A
PloS one 2016;11(1):e0147312
PloS one 2016;11(1):e0147312
Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
Lund AW, Wagner M, Fankhauser M, Steinskog ES, Broggi MA, Spranger S, Gajewski TF, Alitalo K, Eikesdal HP, Wiig H, Swartz MA
The Journal of clinical investigation 2016 Sep 1;126(9):3389-402
The Journal of clinical investigation 2016 Sep 1;126(9):3389-402
Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts.
Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D'Alessio A, Maiorana A, Palmieri V, Papi M, De Spirito M, Di Leone A, Masetti R, Sica G
British journal of cancer 2015 May 12;112(10):1675-86
British journal of cancer 2015 May 12;112(10):1675-86
Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.
Gonzalez-Valdes I, Hidalgo I, Bujarrabal A, Lara-Pezzi E, Padron-Barthe L, Garcia-Pavia P, Gómez-del Arco P, Redondo JM, Ruiz-Cabello JM, Jimenez-Borreguero LJ, Enriquez JA, de la Pompa JL, Hidalgo A, Gonzalez S
Nature communications 2015 Mar 9;6:6473
Nature communications 2015 Mar 9;6:6473
Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment.
Zhang P, Lo A, Huang Y, Huang G, Liang G, Mott J, Karpen GH, Blakely EA, Bissell MJ, Barcellos-Hoff MH, Snijders AM, Mao JH
Scientific reports 2015 Mar 9;5:8919
Scientific reports 2015 Mar 9;5:8919
CD4(+)Foxp3(+) Tregs protect against innate immune cell-mediated fulminant hepatitis in mice.
Hou X, Song J, Su J, Huang D, Gao W, Yan J, Shen J
Molecular immunology 2015 Feb;63(2):420-7
Molecular immunology 2015 Feb;63(2):420-7
Emdogain-regulated gene expression in palatal fibroblasts requires TGF-βRI kinase signaling.
Stähli A, Bosshardt D, Sculean A, Gruber R
PloS one 2014;9(9):e105672
PloS one 2014;9(9):e105672
Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-β and induce Tregs development via TGF-β.
Xu S, Zhu J, Wu Z
PloS one 2014;9(3):e91709
PloS one 2014;9(3):e91709
Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF.
Bernard M, Dieudé M, Yang B, Hamelin K, Underwood K, Hébert MJ
Autophagy 2014;10(12):2193-207
Autophagy 2014;10(12):2193-207
Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor β (TGFβ)-, epidermal growth factor (EGF)-, and nuclear factor κB (NFκB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion.
Kang I, Yoon DW, Braun KR, Wight TN
The Journal of biological chemistry 2014 May 30;289(22):15393-404
The Journal of biological chemistry 2014 May 30;289(22):15393-404
Platelets provoke distinct dynamics of immune responses by differentially regulating CD4+ T-cell proliferation.
Zhu L, Huang Z, Stålesen R, Hansson GK, Li N
Journal of thrombosis and haemostasis : JTH 2014 Jul;12(7):1156-65
Journal of thrombosis and haemostasis : JTH 2014 Jul;12(7):1156-65
IL-2/anti-IL-2 complex attenuates renal ischemia-reperfusion injury through expansion of regulatory T cells.
Kim MG, Koo TY, Yan JJ, Lee E, Han KH, Jeong JC, Ro H, Kim BS, Jo SK, Oh KH, Surh CD, Ahn C, Yang J
Journal of the American Society of Nephrology : JASN 2013 Oct;24(10):1529-36
Journal of the American Society of Nephrology : JASN 2013 Oct;24(10):1529-36
Toll-like receptor 2 (TLR2), transforming growth factor-β, hyaluronan (HA), and receptor for HA-mediated motility (RHAMM) are required for surfactant protein A-stimulated macrophage chemotaxis.
Foley JP, Lam D, Jiang H, Liao J, Cheong N, McDevitt TM, Zaman A, Wright JR, Savani RC
The Journal of biological chemistry 2012 Oct 26;287(44):37406-19
The Journal of biological chemistry 2012 Oct 26;287(44):37406-19
Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis.
Lauzier A, Charbonneau M, Paquette M, Harper K, Dubois CM
Arthritis research & therapy 2012 Jul 4;14(4):R159
Arthritis research & therapy 2012 Jul 4;14(4):R159
Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade.
Olson BM, Jankowska-Gan E, Becker JT, Vignali DA, Burlingham WJ, McNeel DG
Journal of immunology (Baltimore, Md. : 1950) 2012 Dec 15;189(12):5590-601
Journal of immunology (Baltimore, Md. : 1950) 2012 Dec 15;189(12):5590-601
IL-33 induces IL-9 production in human CD4+ T cells and basophils.
Blom L, Poulsen BC, Jensen BM, Hansen A, Poulsen LK
PloS one 2011;6(7):e21695
PloS one 2011;6(7):e21695
Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.
Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y
The Journal of clinical investigation 2011 Nov;121(11):4548-66
The Journal of clinical investigation 2011 Nov;121(11):4548-66
Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche.
Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H
Cell 2011 Nov 23;147(5):1146-58
Cell 2011 Nov 23;147(5):1146-58
The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace WW, Fagarasan S
Immunity 2010 Jul 23;33(1):71-83
Immunity 2010 Jul 23;33(1):71-83
Interferon-gamma and the interferon-inducible chemokine CXCL10 protect against aneurysm formation and rupture.
King VL, Lin AY, Kristo F, Anderson TJ, Ahluwalia N, Hardy GJ, Owens AP 3rd, Howatt DA, Shen D, Tager AM, Luster AD, Daugherty A, Gerszten RE
Circulation 2009 Jan 27;119(3):426-35
Circulation 2009 Jan 27;119(3):426-35
Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling.
Shintani Y, Maeda M, Chaika N, Johnson KR, Wheelock MJ
American journal of respiratory cell and molecular biology 2008 Jan;38(1):95-104
American journal of respiratory cell and molecular biology 2008 Jan;38(1):95-104
Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
Akool el-S, Doller A, Babelova A, Tsalastra W, Moreth K, Schaefer L, Pfeilschifter J, Eberhardt W
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2831-45
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2831-45
Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
Akool el-S, Doller A, Babelova A, Tsalastra W, Moreth K, Schaefer L, Pfeilschifter J, Eberhardt W
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2831-45
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2831-45
Local administration of interleukin-11 ameliorates intestinal radiation injury in rats.
Boerma M, Wang J, Burnett AF, Santin AD, Roman JJ, Hauer-Jensen M
Cancer research 2007 Oct 1;67(19):9501-6
Cancer research 2007 Oct 1;67(19):9501-6
Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease.
Alcorn JF, Rinaldi LM, Jaffe EF, van Loon M, Bates JH, Janssen-Heininger YM, Irvin CG
American journal of respiratory and critical care medicine 2007 Nov 15;176(10):974-82
American journal of respiratory and critical care medicine 2007 Nov 15;176(10):974-82
Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.
Cohn RD, van Erp C, Habashi JP, Soleimani AA, Klein EC, Lisi MT, Gamradt M, ap Rhys CM, Holm TM, Loeys BL, Ramirez F, Judge DP, Ward CW, Dietz HC
Nature medicine 2007 Feb;13(2):204-10
Nature medicine 2007 Feb;13(2):204-10
Increase in transforming growth factor-beta in the brain during infection is related to fever, not depression of spontaneous motor activity.
Matsumura S, Shibakusa T, Fujikawa T, Yamada H, Inoue K, Fushiki T
Neuroscience 2007 Feb 9;144(3):1133-40
Neuroscience 2007 Feb 9;144(3):1133-40
Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?
McLennan SV, Kelly DJ, Schache M, Waltham M, Dy V, Langham RG, Yue DK, Gilbert RE
Kidney international 2007 Aug;72(4):481-8
Kidney international 2007 Aug;72(4):481-8
Uptake of host cell transforming growth factor-beta by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion.
Waghabi MC, Keramidas M, Bailly S, Degrave W, Mendonça-Lima L, Soeiro Mde N, Meirelles Mde N, Paciornik S, Araújo-Jorge TC, Feige JJ
The American journal of pathology 2005 Oct;167(4):993-1003
The American journal of pathology 2005 Oct;167(4):993-1003
Uptake of host cell transforming growth factor-beta by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion.
Waghabi MC, Keramidas M, Bailly S, Degrave W, Mendonça-Lima L, Soeiro Mde N, Meirelles Mde N, Paciornik S, Araújo-Jorge TC, Feige JJ
The American journal of pathology 2005 Oct;167(4):993-1003
The American journal of pathology 2005 Oct;167(4):993-1003
Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.
Akool el-S, Doller A, Müller R, Gutwein P, Xin C, Huwiler A, Pfeilschifter J, Eberhardt W
The Journal of biological chemistry 2005 Nov 25;280(47):39403-16
The Journal of biological chemistry 2005 Nov 25;280(47):39403-16
Thrombospondin plays a vital role in the immune privilege of the eye.
Zamiri P, Masli S, Kitaichi N, Taylor AW, Streilein JW
Investigative ophthalmology & visual science 2005 Mar;46(3):908-19
Investigative ophthalmology & visual science 2005 Mar;46(3):908-19
Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice.
Mesplès B, Fontaine RH, Lelièvre V, Launay JM, Gressens P
Neurobiology of disease 2005 Feb;18(1):193-205
Neurobiology of disease 2005 Feb;18(1):193-205
Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity.
Gilchrist RB, Ritter LJ, Cranfield M, Jeffery LA, Amato F, Scott SJ, Myllymaa S, Kaivo-Oja N, Lankinen H, Mottershead DG, Groome NP, Ritvos O
Biology of reproduction 2004 Sep;71(3):732-9
Biology of reproduction 2004 Sep;71(3):732-9
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Torrealba JR, Katayama M, Fechner JH Jr, Jankowska-Gan E, Kusaka S, Xu Q, Schultz JM, Oberley TD, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5753-64
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5753-64
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Torrealba JR, Katayama M, Fechner JH Jr, Jankowska-Gan E, Kusaka S, Xu Q, Schultz JM, Oberley TD, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5753-64
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5753-64
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5213-21
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5213-21
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5213-21
Journal of immunology (Baltimore, Md. : 1950) 2004 May 1;172(9):5213-21
Effect of weightbearing on bone formation during distraction osteogenesis.
Leung KS, Cheung WH, Yeung HY, Lee KM, Fung KP
Clinical orthopaedics and related research 2004 Feb;(419):251-7
Clinical orthopaedics and related research 2004 Feb;(419):251-7
Effect of weightbearing on bone formation during distraction osteogenesis.
Leung KS, Cheung WH, Yeung HY, Lee KM, Fung KP
Clinical orthopaedics and related research 2004 Feb;(419):251-7
Clinical orthopaedics and related research 2004 Feb;(419):251-7
Connective tissue growth factor and its correlation to other growth factors in experimental granulation tissue.
Inkinen K, Wolff H, Lindroos P, Ahonen J
Connective tissue research 2003;44(1):19-29
Connective tissue research 2003;44(1):19-29
Estrogen inhibition of PTH-stimulated osteoclast formation and attachment in vitro: involvement of both PKA and PKC.
Liu BY, Wu PW, Bringhurst FR, Wang JT
Endocrinology 2002 Feb;143(2):627-35
Endocrinology 2002 Feb;143(2):627-35
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- TGF-beta 1 Inhibition of IL-4-dependent Cell Proliferation and Neutralization by TGF-beta Antibody. Porcine TGF-beta 1 (Catalog # 101-B1) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Mouse IL-4 (7.5 ng/mL) activity elicited by Porcine TGF-beta 1 (1 ng/mL) is neutralized (green line) by increasing concentrations of TGF-beta Pan Specific Polyclonal Antibody (Catalog # AB-100-NA). The ND50 range is 5-30 µg/mL.
