NBP2-47736FR

antibody from Novus Biologicals

Targeting: TGFB1 CED, DPD1, TGFB, TGFbeta

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

NBP2-47736FR

Provider

Novus Biologicals

Product name

Mouse Monoclonal TGF-beta Antibody

Antibody type

Monoclonal

Description

Protein A or G purified. This MAb recognizes TGF beta 1, 2 and 3. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFbeta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.

Reactivity

Human, Mouse, Rat, Bovine, Canine, Hamster, Simian

Host

Mouse

Conjugate

Near infrared dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.