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LearnMAB6841
antibody from R&D Systems
Targeting: FGFR2
BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- MAB6841 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human FGF R2 alpha Monoclonal Antibody (Clone 98706)
- Antibody type
- Monoclonal
- Antigen
- S. frugiperda insect ovarian cell line Sf 21-derived recombinant human FGF R2 isoforms and Mouse myeloma cell line NS0-derived recombinant human FGF R2 isoforms
- Description
- Protein A or G purified from ascites
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Acquired resistance to LY2874455 in FGFR2-amplified gastric cancer through an emergence of novel FGFR2-ACSL5 fusion.
FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.
Kim SY, Ahn T, Bang H, Ham JS, Kim J, Kim ST, Jang J, Shim M, Kang SY, Park SH, Min BH, Lee H, Kang WK, Kim KM, Park W, Lee J
Oncotarget 2017 Feb 28;8(9):15014-15022
Oncotarget 2017 Feb 28;8(9):15014-15022
FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
Mathur A, Ware C, Davis L, Gazdar A, Pan BS, Lutterbach B
PloS one 2014;9(6):e98515
PloS one 2014;9(6):e98515
FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.
Kunii K, Davis L, Gorenstein J, Hatch H, Yashiro M, Di Bacco A, Elbi C, Lutterbach B
Cancer research 2008 Apr 1;68(7):2340-8
Cancer research 2008 Apr 1;68(7):2340-8
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