Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- orb137977 - Provider product page
- Provider
- Biorbyt
- Product name
- ANGPT1 antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal to ANGPT1. Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Storage
- Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
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Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Western blot analysis of Lane 1: Rat Heart Tissue Lysate, Lane 2: Rat Brain Tissue Lysate, Lane 3: Rat Kidney Tissue Lysate, Lane 4: SMMC Whole Cell Lysate using ANGPT1 antibody
Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of formalin-fixed paraffin embedded Human Lung Cancer Tissue using ANGPT1 antibody