AFC-544CL

antibody from Creative Biolabs

Targeting: SHH HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS

No application information provided.

Antibody Data

Product number

AFC-544CL

Provider

Creative Biolabs

Product name

Afuco? Anti-Human SHH ADCC Recombinant Antibody (MEDI-5304), ADCC Enhanced

Antibody type

Monoclonal

Description

Anti-SHH ADCC Enhanced Antibody (MEDI-5304) is an ADCC enhanced antibody produced by our Afuco? platform. MEDI-5304 is the first fully human hedgehog antibody which inhibited transcription of hedgehog target genes and osteoblast differentiation of C3H10T1/2 cells. MEDI-5304 represents a potent dual hedgehog inhibitor suitable for continued development to evaluate efficacy and safety in human patients with tumors harboring elevated levels of SHH or IHH.

Reactivity

Human

Storage

4 ¡ãC, -20¡ãC if preferred