ABIN1545520

antibody from antibodies-online

Targeting: BRCA1 BRCC1, FANCS, PPP1R53, RNF53

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1545520

Provider

antibodies-online

Product name

anti-Breast Cancer 1 (BRCA1) (N-Term) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide directed towards the N terminal of human BRCA1

Description

Affinity Purified

Reactivity

Human, Rat, Canine

Host

Rabbit

Antigen sequence

MDLSALRVEEVQNVINAMQKILECPICLELIKEPV
STKCD HIFCKFCMLK


Epitope

N-Term

Vial size

50 μg

Concentration

1mg/mL

Storage

-20°C

Handling

Avoid repeated freeze-thaw cycles.

References

Submitted references

Lymphocyte infiltration, expression of interleukin (IL) -1, IL-6 and expression of mutated breast cancer susceptibility gene-1 correlate with malignancy of canine mammary tumours.

Kim JH, Yu CH, Yhee JY, Im KS, Sur JH
Journal of comparative pathology 2010 Feb-Apr;142(2-3):177-86

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Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?

Mark WY, Liao JC, Lu Y, Ayed A, Laister R, Szymczyna B, Chakrabartty A, Arrowsmith CH
Journal of molecular biology 2005 Jan 14;345(2):275-87

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB Suggested Antibody Titration: 0.2-1 μg/mL Positive Control: K562BRCA1 is supported by BioGPS gene expression data to be expressed in K562