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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN497964 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Autophagy Related 12 (ATG12) (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- A 15 amino acid peptide from near the center of Human ATG12
- Description
- Affinity Chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Middle Region
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C. Antibodies should not be exposed to prolonged high temperatures.
Submitted references The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.
The Atg5 Atg12 conjugate associates with innate antiviral immune responses.
Autophagy as a cell death and tumor suppressor mechanism.
The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification.
Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y
The Journal of biological chemistry 2007 Dec 28;282(52):37298-302
The Journal of biological chemistry 2007 Dec 28;282(52):37298-302
The Atg5 Atg12 conjugate associates with innate antiviral immune responses.
Jounai N, Takeshita F, Kobiyama K, Sawano A, Miyawaki A, Xin KQ, Ishii KJ, Kawai T, Akira S, Suzuki K, Okuda K
Proceedings of the National Academy of Sciences of the United States of America 2007 Aug 28;104(35):14050-5
Proceedings of the National Academy of Sciences of the United States of America 2007 Aug 28;104(35):14050-5
Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906
Oncogene 2004 Apr 12;23(16):2891-906
The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification.
Nemoto T, Tanida I, Tanida-Miyake E, Minematsu-Ikeguchi N, Yokota M, Ohsumi M, Ueno T, Kominami E
The Journal of biological chemistry 2003 Oct 10;278(41):39517-26
The Journal of biological chemistry 2003 Oct 10;278(41):39517-26
Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO
Carcinogenesis 1993 Dec;14(12):2501-5
Carcinogenesis 1993 Dec;14(12):2501-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot. AP20048PU-N ATG12 antibody staining of Mouse heart tissue lysate at 1 μg/ml. A: Absence of Blocking peptide B: Presence of Blocking peptide
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry: AP20048PU-N ATG12 antibody staining of Human brain tissue at 2.5 ?g/ml.
