ABIN1001830

antibody from antibodies-online

Targeting: ATG12 APG12, APG12L

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1001830

Provider

antibodies-online

Product name

anti-Autophagy Related 12 (ATG12) (Internal Region) antibody

Antibody type

Polyclonal

Antigen

ATG12 antibody was raised in rabbits against a 15 amino acid peptide from near the center of human ATG12.

Description

Affinity chromatography purified via peptide column.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Internal Region

Isotype

IgG

Vial size

100 μg

Storage

4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.

References

Submitted references

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.

Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y
The Journal of biological chemistry 2007 Dec 28;282(52):37298-302

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Autophagy as a cell death and tumor suppressor mechanism.

Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906

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Tor-mediated induction of autophagy via an Apg1 protein kinase complex.

Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y
The Journal of cell biology 2000 Sep 18;150(6):1507-13

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Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.

Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO
Carcinogenesis 1993 Dec;14(12):2501-5