Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN307123 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- F38 P7 H9
- Vial size
- 200 µg
- Storage
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Submitted references AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC.
The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling.
Marie S, Heron B, Bitoun P, Timmerman T, Van Den Berghe G, Vincent MF
American journal of human genetics 2004 Jun;74(6):1276-81
American journal of human genetics 2004 Jun;74(6):1276-81
The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling.
Bulock KG, Beardsley GP, Anderson KS
The Journal of biological chemistry 2002 Jun 21;277(25):22168-74
The Journal of biological chemistry 2002 Jun 21;277(25):22168-74
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Left and Center: Immunohistochemical staining of normal colon tissue and colon carcinoma tissue using ATIC antibody . Right: Western blot using ATIC antibody on HT29 cell lysate. Human, Frog, Fruit Fly, Rat, Mouse