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antibody from antibodies-online
Targeting: FOXP3
AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [2]
- Immunohistochemistry [1]
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- Product number
- ABIN153185 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Forkhead Box P3 (FOXP3) (AA 400-431), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term, AA 400-431
- Vial size
- 0.1 mL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references Compartmentalization of immune responses in human tuberculosis: few CD8+ effector T cells but elevated levels of FoxP3+ regulatory t cells in the granulomatous lesions.
Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta.
Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells.
FOXP3 acts as a rheostat of the immune response.
Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment.
Rahman S, Gudetta B, Fink J, Granath A, Ashenafi S, Aseffa A, Derbew M, Svensson M, Andersson J, Brighenti SG
The American journal of pathology 2009 Jun;174(6):2211-24
The American journal of pathology 2009 Jun;174(6):2211-24
Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta.
Ostroukhova M, Qi Z, Oriss TB, Dixon-McCarthy B, Ray P, Ray A
The Journal of clinical investigation 2006 Apr;116(4):996-1004
The Journal of clinical investigation 2006 Apr;116(4):996-1004
Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells.
Ochando JC, Yopp AC, Yang Y, Garin A, Li Y, Boros P, Llodra J, Ding Y, Lira SA, Krieger NR, Bromberg JS
Journal of immunology (Baltimore, Md. : 1950) 2005 Jun 1;174(11):6993-7005
Journal of immunology (Baltimore, Md. : 1950) 2005 Jun 1;174(11):6993-7005
FOXP3 acts as a rheostat of the immune response.
Ochs HD, Ziegler SF, Torgerson TR
Immunological reviews 2005 Feb;203:156-64
Immunological reviews 2005 Feb;203:156-64
Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment.
Polanczyk MJ, Carson BD, Subramanian S, Afentoulis M, Vandenbark AA, Ziegler SF, Offner H
Journal of immunology (Baltimore, Md. : 1950) 2004 Aug 15;173(4):2227-30
Journal of immunology (Baltimore, Md. : 1950) 2004 Aug 15;173(4):2227-30
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Sample: Healthy thymus from a C57BL/6 mouse
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Incubated only with CD4 and no Foxp3
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
