orb150892

OCRL antibody from Biorbyt
Dent-2, OCRL1

Antibody data

Product number
orb150892
Provider
Biorbyt
Product name
OCRL antibody
Provider product page
Biorbyt - orb150892
Antibody type
Monoclonal
Description
Mouse monoclonal to OCRL (Unconjugated). Inositol polyphosphate 5-phosphatase OCRL-1 (ORCL) is also called Lowe oculocerebrorenal syndrome protein. ORCL is a phosphotase that converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate, as well as inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. ORCL is involved in primary cilia assembly and may also have a role in lysosomal membrane trafficking. ORCL is expressed in brain, skeletal muscle, heart, kidney, lung, placenta, fibroblasts, retina and the retinal pigment epithelium. OCRL defects can cause Lowe oculocerebrorenal syndrome (OCRL) and Dent disease type 2 (DD2)..
Reactivity
Human, Rat
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
S166A-26
Vial size
100 μg
Concentration
1 mg/ml
Storage
Store at 2-8°C and -20°C for one year. (Shipped on ice packs)
Provider Type Product Number
- No reagents -