Antibody data
- Antibody Data
- Antigen structure
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- Product number
- orb167671 - Provider product page
- Provider
- Biorbyt
- Product name
- INPP5b antibody (Streptavidin)
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody to INPP5b (Streptavidin). Inositol polyphosphate 5-phosphatase OCRL-1 (ORCL) is also called Lowe oculocerebrorenal syndrome protein. ORCL is a phosphotase that converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate, as well as inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. ORCL is involved in primary cilia assembly and may also have a role in lysosomal membrane trafficking. ORCL is expressed in brain, skeletal muscle, heart, kidney, lung, placenta, fibroblasts, retina and the retinal pigment epithelium. OCRL defects can cause Lowe oculocerebrorenal syndrome (OCRL) and Dent disease type 2 (DD2).
- Reactivity
- Human, Rat
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- S166A-26
- Vial size
- 100 μg
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C.
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