ABIN2484475

antibody from antibodies-online

Targeting: AHSA1 Aha1, C14orf3, hAha1, p38

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN2484475

Provider

antibodies-online

Product name

anti-AHA1, Activator of Heat Shock 90kDa Protein ATPase Homolog 1 (Yeast) (AHSA1) antibody (FITC)

Antibody type

Polyclonal

Description

Protein A Purified

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Green dye

Vial size

100 μL

Storage

-20°C

References

Submitted references

The charged linker region is an important regulator of Hsp90 function.

Hainzl O, Lapina MC, Buchner J, Richter K
The Journal of biological chemistry 2009 Aug 21;284(34):22559-67

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A novel HSP90 chaperone complex regulates intracellular vesicle transport.

Lotz GP, Brychzy A, Heinz S, Obermann WM
Journal of cell science 2008 Mar 1;121(Pt 5):717-23

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Silencing of HSP90 cochaperone AHA1 expression decreases client protein activation and increases cellular sensitivity to the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin.

Holmes JL, Sharp SY, Hobbs S, Workman P
Cancer research 2008 Feb 15;68(4):1188-97

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Aha1 competes with Hop, p50 and p23 for binding to the molecular chaperone Hsp90 and contributes to kinase and hormone receptor activation.

Harst A, Lin H, Obermann WM
The Biochemical journal 2005 May 1;387(Pt 3):789-96

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB