CABT-BL7799

antibody from Creative Diagnostics

Targeting: IL3RA CD123

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL7799

Provider

Creative Diagnostics

Product name

Anti-IL3RA Monoclonal antibody, clone 7I7 [PE/Cy7?]

Antibody type

Monoclonal

Description

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. It is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. It is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.

Reactivity

Human

Host

Mouse

Isotype

IgG