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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 353738 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#353738, RRID:AB_2565924
- Product name
- Brilliant Violet 785™ anti-human CD183 (CXCR3)
- Antibody type
- Monoclonal
- Antigen
- Human CXCR3 transfectants
- Description
- Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Near infrared dye
- Antibody clone number
- G025H7
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained with CD3 PerCP/Cy5.5 and CD183 (clone G025H7) Brilliant Violet 785™ (top image) or mouse IgG1, κ Brilliant Violet 785™ (bottom image).
- Conjugate
- Near infrared dye
