62-1839-41

antibody from Invitrogen Antibodies
Targeting: CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR
Provider product page for 62-1839-41

Antibody data

Product number
62-1839-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD183 (CXCR3) Monoclonal Antibody (CEW33D), Super Bright 436, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The CEW33D monoclonal antibody reacts with human CD183. CD183, also known as CXCR3, is a G protein-coupled chemokine receptor that interacts with ligands CXCL9 (MIG), CXCL10 (IP-10), and CXCL11 (I-TAC). Strongly associated with type 1 immunity, CD183 is induced in naive T cells upon activation and remains upregulated in T helper type (Th)1 cells, CD8 effector cells, NK cells and NKT cells. CD183-ligand interactions mediate infiltration of inflamed tissues in normal type 1 immune responses as well as in many inflammatory and autoimmune diseases. CD183 is also expressed on some B cells and plasmacytoid DC. Applications Reported: This CEW33D antibody has been reported for use in flow cytometric analysis. Applications Tested: This CEW33D antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 105 to 108 cells/test. Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (cat. SB-4400) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information. Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
CEW33D
Vial size
25 Tests
Concentration
5 µl/Test
Storage
4° C, store in dark, DO NOT FREEZE!
CXCR3 protein structure - 62-1839-41 shown in red.