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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [18]
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- Immunohistochemistry [1]
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- Product number
- MA5-11213 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-HSP27 Monoclonal Antibody (G3.1), Biotin
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- MA5-11231 targets MMP-11 (Stromelysin-3) in IHC (P), IP, and WB applications and shows reactivity with Human samples. The MA5-11231 immunogen is recombinant protein corresponding to active form of human MMP-11.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- G3.1
- Vial size
- 500 µL
- Concentration
- 0.2 mg/ml
- Storage
- 4° C
Submitted references Multiplexed high content screening reveals that cigarette smoke condensate-altered cell signaling pathways are accentuated through FAK inhibition in human bronchial cells.
Altered expression of HSP27 and HSP70 in distal oesophageal mucosa in patients with gastro-oesophageal reflux disease subjected to fundoplication.
[The effect of resistance-related proteins on the prognosis and survival of patients with osteosarcoma: an immunohistochemical analysis].
Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis.
Expressions of HSP70 and HSP27 in hepatocellular carcinoma.
Expressions of HSP70 and HSP27 in hepatocellular carcinoma.
The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells.
Electromagnetic fields at mobile phone frequency induce apoptosis and inactivation of the multi-chaperone complex in human epidermoid cancer cells.
Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production.
Down-regulation of heat shock protein 27 in neuronal cells and non-neuronal cells expressing mutant ataxin-3.
Expression of heat-shock proteins hsp27, hsp70 and hsp90 in malignant epithelial tumour of the ovaries.
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.
Differential proteome analysis of replicative senescence in rat embryo fibroblasts.
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease.
The Fas-induced apoptosis analyzed by high throughput proteome analysis.
Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas.
Heat shock proteins hsp27 and hsp70: lack of correlation with response to tamoxifen and clinical course of disease in estrogen receptor-positive metastatic breast cancer (a Southwest Oncology Group Study).
Expression of heat shock proteins in squamous cell carcinoma of the tongue: an immunohistochemical study.
Carter CA
International journal of toxicology 2012 Jun;31(3):257-66
International journal of toxicology 2012 Jun;31(3):257-66
Altered expression of HSP27 and HSP70 in distal oesophageal mucosa in patients with gastro-oesophageal reflux disease subjected to fundoplication.
Rantanen T, Honkanen T, Paavonen T, Rantanen L, Oksala N
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2011 Feb;37(2):168-74
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2011 Feb;37(2):168-74
[The effect of resistance-related proteins on the prognosis and survival of patients with osteosarcoma: an immunohistochemical analysis].
Ozger H, Eralp L, Atalar AC, Toker B, Esberk Ateş L, Sungur M, Bilgiç B, Ayan I
Acta orthopaedica et traumatologica turcica 2009 Jan-Feb;43(1):28-34
Acta orthopaedica et traumatologica turcica 2009 Jan-Feb;43(1):28-34
Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis.
Liu Y, Liu H, Han B, Zhang JT
Cancer research 2006 Mar 15;66(6):3248-55
Cancer research 2006 Mar 15;66(6):3248-55
Expressions of HSP70 and HSP27 in hepatocellular carcinoma.
Joo M, Chi JG, Lee H
Journal of Korean medical science 2005 Oct;20(5):829-34
Journal of Korean medical science 2005 Oct;20(5):829-34
Expressions of HSP70 and HSP27 in hepatocellular carcinoma.
Joo M, Chi JG, Lee H
Journal of Korean medical science 2005 Oct;20(5):829-34
Journal of Korean medical science 2005 Oct;20(5):829-34
The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells.
Sommer S, Cui Y, Brewer G, Fuqua SA
The Journal of steroid biochemistry and molecular biology 2005 Nov;97(3):219-29
The Journal of steroid biochemistry and molecular biology 2005 Nov;97(3):219-29
Electromagnetic fields at mobile phone frequency induce apoptosis and inactivation of the multi-chaperone complex in human epidermoid cancer cells.
Caraglia M, Marra M, Mancinelli F, D'Ambrosio G, Massa R, Giordano A, Budillon A, Abbruzzese A, Bismuto E
Journal of cellular physiology 2005 Aug;204(2):539-48
Journal of cellular physiology 2005 Aug;204(2):539-48
Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production.
Pignatelli D, Ferreira J, Soares P, Costa MJ, Magalhães MC
Microscopy research and technique 2003 Jun 15;61(3):315-23
Microscopy research and technique 2003 Jun 15;61(3):315-23
Down-regulation of heat shock protein 27 in neuronal cells and non-neuronal cells expressing mutant ataxin-3.
Wen FC, Li YH, Tsai HF, Lin CH, Li C, Liu CS, Lii CK, Nukina N, Hsieh M
FEBS letters 2003 Jul 10;546(2-3):307-14
FEBS letters 2003 Jul 10;546(2-3):307-14
Expression of heat-shock proteins hsp27, hsp70 and hsp90 in malignant epithelial tumour of the ovaries.
Elpek GO, Karaveli S, Simşek T, Keles N, Aksoy NH
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003 Apr;111(4):523-30
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003 Apr;111(4):523-30
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.
Wyttenbach A, Sauvageot O, Carmichael J, Diaz-Latoud C, Arrigo AP, Rubinsztein DC
Human molecular genetics 2002 May 1;11(9):1137-51
Human molecular genetics 2002 May 1;11(9):1137-51
Differential proteome analysis of replicative senescence in rat embryo fibroblasts.
Benvenuti S, Cramer R, Quinn CC, Bruce J, Zvelebil M, Corless S, Bond J, Yang A, Hockfield S, Burlingame AL, Waterfield MD, Jat PS
Molecular & cellular proteomics : MCP 2002 Apr;1(4):280-92
Molecular & cellular proteomics : MCP 2002 Apr;1(4):280-92
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease.
Wyttenbach A, Swartz J, Kita H, Thykjaer T, Carmichael J, Bradley J, Brown R, Maxwell M, Schapira A, Orntoft TF, Kato K, Rubinsztein DC
Human molecular genetics 2001 Aug 15;10(17):1829-45
Human molecular genetics 2001 Aug 15;10(17):1829-45
The Fas-induced apoptosis analyzed by high throughput proteome analysis.
Gerner C, Frohwein U, Gotzmann J, Bayer E, Gelbmann D, Bursch W, Schulte-Hermann R
The Journal of biological chemistry 2000 Dec 15;275(50):39018-26
The Journal of biological chemistry 2000 Dec 15;275(50):39018-26
Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas.
Soldes OS, Kuick RD, Thompson IA 2nd, Hughes SJ, Orringer MB, Iannettoni MD, Hanash SM, Beer DG
British journal of cancer 1999 Feb;79(3-4):595-603
British journal of cancer 1999 Feb;79(3-4):595-603
Heat shock proteins hsp27 and hsp70: lack of correlation with response to tamoxifen and clinical course of disease in estrogen receptor-positive metastatic breast cancer (a Southwest Oncology Group Study).
Ciocca DR, Green S, Elledge RM, Clark GM, Pugh R, Ravdin P, Lew D, Martino S, Osborne CK
Clinical cancer research : an official journal of the American Association for Cancer Research 1998 May;4(5):1263-6
Clinical cancer research : an official journal of the American Association for Cancer Research 1998 May;4(5):1263-6
Expression of heat shock proteins in squamous cell carcinoma of the tongue: an immunohistochemical study.
Ito T, Kawabe R, Kurasono Y, Hara M, Kitamura H, Fujita K, Kanisawa M
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1998 Jan;27(1):18-22
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1998 Jan;27(1):18-22
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human breast carcinoma stained with Heat Shock Protein 27 Ab-1 using peroxidase-conjugate and DAB chromogen. Note intense cytoplasmic staining of tumor cells.
- Conjugate
- Biotin
