orb76202

antibody from Biorbyt

Targeting: STAT6 D12S1644, IL-4-STAT

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Validation data

Product number: orb76202 - Provider product page
Provider: Biorbyt
Product name: Anti-Stat6 antibody
Antibody type: Polyclonal
Description: Rabbit Polyclonal to Stat6. STAT6 is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors. The gene spans 19 kb and contains 23 exons. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Vial size: 100 μg
Concentration: 0.1-0.5 μg/ml
Storage: Store at -20°C for one year.After reconstitution, at 4°C. for one month. It can also be aliquotted and stored frozen at -20°C. for a longer time.Avoid repeated freezing and thawing.

STAT6 protein structure - orb76202 shown in red.