Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- orb76205 - Provider product page
- Provider
- Biorbyt
- Product name
- Anti-Stat6 antibody
- Antibody type
- Polyclonal
- Description
- Rabbit Polyclonal to Stat6. STAT6 is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors. The gene spans 19 kb and contains 23 exons. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 100 μg
- Concentration
- 0.1-0.5 μg/ml,0.5-1 μg/ml
- Storage
- Store at -20°C for one year.After reconstitution, at 4°C. for one month. It can also be aliquotted and stored frozen at -20°C. for a longer time.Avoid repeated freezing and thawing.
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Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Western blot analysis of Lane 1: Rat Testis Tissue Lysate, Lane 2: Rat Ovary Tissue Lysate, Lane 3: Mouse Testis Tissue Lysate, Lane 4: Mouse Ovary Tissue Lysate, Lane 5: HELA Cell Lysate, Lane 6: SKOV Cell Lysate using Stat6 antibody
Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of formalin-fixed paraffin embedded Human Intestinal Cancer Tissue using Stat6 antibody