BS4622

antibody from Bioworld Technology, Inc
Targeting: PRKCD
Provider product page for BS4622
Western blot
Immunohistochemistry

Antibody data

Product number
BS4622 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PKC Ñ´ (phospho S645) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human PKC Ñ´ around the phosphorylation site of Serine 645.
Description
Protein Kinase C delta (PKC delta) is a 78 kDa member of the novel group (nPKCs: sensitive to diacylglycerol, phosphatidylserine, and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC delta is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of multiple cellular processes including cell cycle progression and apoptosis. Autophosphorylation of serine 664 (serine 662 in mouse and rat) contributes to PKC delta activity. Serum dependent phosphorylation of serine 664 is mediated by mTOR pathway, is protected from dephosphorylation by phosphorylated threonine 505 in the activation loop, and is implicated in prolactin signaling.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PRKCD protein structure - BS4622 shown in red.