ABIN197375

antibody from antibodies-online

Targeting: VAV1 VAV

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN197375

Provider

antibodies-online

Product name

anti-Vav 1 Oncogene (VAV1) (Tyr174) antibody

Antibody type

Polyclonal

Description

Immunoaffinity chromatography.

Reactivity

Human, Rat

Host

Rabbit

Epitope

Tyr174

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain.

Amarasinghe GK, Rosen MK
Biochemistry 2005 Nov 22;44(46):15257-68

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Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.

Charvet C, Canonigo AJ, Billadeau DD, Altman A
The Journal of biological chemistry 2005 Apr 15;280(15):15289-99

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Cbl-mediated ubiquitinylation and negative regulation of Vav.

Miura-Shimura Y, Duan L, Rao NL, Reddi AL, Shimura H, Rottapel R, Druker BJ, Tsygankov A, Band V, Band H
The Journal of biological chemistry 2003 Oct 3;278(40):38495-504

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A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation.

Kuhne MR, Ku G, Weiss A
The Journal of biological chemistry 2000 Jan 21;275(3):2185-90