NBP2-47775UV

antibody from Novus Biologicals
Targeting: ZAP70 SRK, STD, ZAP-70
Provider product page for NBP2-47775UV
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NBP2-47775UV - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal ZAP70 Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. ZAP70 is a 70kDa protein tyrosine kinase found in T-cells and natural killer cells.Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well.Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis.
Reactivity
Human
Host
Mouse
Conjugate
Blue dye
Isotype
IgG
Vial size
0.1 ml
Storage
Store at 4C in the dark.
ZAP70 protein structure - NBP2-47775UV shown in red.