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- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN967848 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 468-619) antibody
- Antibody type
- Monoclonal
- Antigen
- Human ZAP-70 Kinase
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 468-619
- Isotype
- IgG
- Antibody clone number
- OPG-01
- Vial size
- 50 μg
- Concentration
- 250 μg/ml
- Storage
- -20°C
Submitted references Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel.
CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.
Differential loss of T cell signaling molecules in metastatic melanoma patients' T lymphocyte subsets expressing distinct TCR variable regions.
Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase.
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency.
Mora AL, Stanley S, Armistead W, Chan AC, Boothby M
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 15;167(10):5628-35
Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 15;167(10):5628-35
CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.
Michel F, Attal-Bonnefoy G, Mangino G, Mise-Omata S, Acuto O
Immunity 2001 Dec;15(6):935-45
Immunity 2001 Dec;15(6):935-45
Differential loss of T cell signaling molecules in metastatic melanoma patients' T lymphocyte subsets expressing distinct TCR variable regions.
Maccalli C, Pisarra P, Vegetti C, Sensi M, Parmiani G, Anichini A
Journal of immunology (Baltimore, Md. : 1950) 1999 Dec 15;163(12):6912-23
Journal of immunology (Baltimore, Md. : 1950) 1999 Dec 15;163(12):6912-23
Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase.
Arpaia E, Shahar M, Dadi H, Cohen A, Roifman CM
Cell 1994 Mar 11;76(5):947-58
Cell 1994 Mar 11;76(5):947-58
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency.
Chan AC, Kadlecek TA, Elder ME, Filipovich AH, Kuo WL, Iwashima M, Parslow TG, Weiss A
Science (New York, N.Y.) 1994 Jun 10;264(5165):1599-601
Science (New York, N.Y.) 1994 Jun 10;264(5165):1599-601
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