ABIN196688

antibody from antibodies-online

Targeting: STAT1 ISGF-3, STAT91

Western blot (Recommended by provider)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN196688

Provider

antibodies-online

Product name

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pTyr701) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human STAT1 around the phosphorylation site of tyrosine 701 (T-G-YP-I-K).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pTyr701

Vial size

0.1 mg

Concentration

1.0 mg/mL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9.

Demoulin JB, Van Roost E, Stevens M, Groner B, Renauld JC
The Journal of biological chemistry 1999 Sep 3;274(36):25855-61

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The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus.

Heim MH
Journal of receptor and signal transduction research 1999 Jan-Jul;19(1-4):75-120

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease.

Durbin JE, Hackenmiller R, Simon MC, Levy DE
Cell 1996 Feb 9;84(3):443-50

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Signaling by the cytokine receptor superfamily: JAKs and STATs.

Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O
Trends in biochemical sciences 1994 May;19(5):222-7