orb12092

antibody from Biorbyt

Targeting: CD55 CR, CROM, DAF, TC

Immunocytochemistry (Recommended by provider)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

orb12092

Provider

Biorbyt

Product name

CD55 antibody (FITC)

Antibody type

Monoclonal

Description

Mouse monoclonal to CD55.COB55 reacts with CD55, a 70 kDa GPI anchored single chain glycoprotein, referred to as decay accelerating factor (DAF). CD55 is widely expressed on hematopoietic cells including erythrocytes and NK cells, as well as on some non-hematopoietic cells. DAF protects cells from damage by autologous complement by preventing the amplification steps of the complement components. A defective PIG-A gene can lead to a deficiency of GPI -liked proteins such as CD55 and an acquired hemolytic anemia. This biological state is called paroxysmal nocturnal hemoglobinuria (PNH). Loss of protective proteins on the cell surface makes the red blood cells of PNH patients sensitive to complement-mediated lysis.

Reactivity

Human

Host

Mouse

Conjugate

Green dye

Isotype

IgG

Antibody clone number

COB55

Vial size

50 Tests, 100 Tests

Storage

Store at 4°C. Do not freeze. Light sensitive material.

Flow cytometry

Supportive validation

Submitted by

Biorbyt (provider)

Main image

Experimental details

Flow cytometric analysis of peripheral blood lymphocytes using CD55 antibody (FITC)