ABIN966122

antibody from antibodies-online

Targeting: PTK2 FADK, FAK, FAK1, PPP1R71

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966122

Provider

antibodies-online

Product name

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr925) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human FAK around the phosphorylation site of tyrosine 925 (K-V-YP-E-N).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pTyr925

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling.

Cherubini A, Hofmann G, Pillozzi S, Guasti L, Crociani O, Cilia E, Di Stefano P, Degani S, Balzi M, Olivotto M, Wanke E, Becchetti A, Defilippi P, Wymore R, Arcangeli A
Molecular biology of the cell 2005 Jun;16(6):2972-83

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p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV.

Sanders MA, Basson MD
The Journal of biological chemistry 2005 Jun 24;280(25):23516-22

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Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase.

Toriumi Y, Hiraoka M, Watanabe M, Yoshida M
FEBS letters 2003 Oct 23;553(3):419-22