NBP1-90020

antibody from Novus Biologicals

Targeting: MRC1 bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NBP1-90020

Provider

Novus Biologicals

Proper citation

Novus Cat#NBP1-90020, RRID:AB_11036359

Product name

Rabbit Polyclonal MMR/CD206/Mannose Receptor Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Specificity of human MMR/CD206/Mannose Receptor antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

Reactivity

Human, Mouse, Porcine, Simian

Host

Rabbit

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

References

Submitted references

Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.

Sun G, Cao Y, Qian C, Wan Z, Zhu J, Guo J, Shi L
Aging 2020 Jan 16;12(2):1114-1127

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Influence of Estrogen Modulation on Glia Activation in a Murine Model of Parkinson's Disease.

Siani F, Greco R, Levandis G, Ghezzi C, Daviddi F, Demartini C, Vegeto E, Fuzzati-Armentero MT, Blandini F
Frontiers in neuroscience 2017;11:306

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Hofbauer cells of M2a, M2b and M2c polarization may regulate feto-placental angiogenesis.

Loegl J, Hiden U, Nussbaumer E, Schliefsteiner C, Cvitic S, Lang I, Wadsack C, Huppertz B, Desoye G
Reproduction (Cambridge, England) 2016 Nov;152(5):447-55

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Clinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin Toxin.

Pincus SH, Bhaskaran M, Brey RN 3rd, Didier PJ, Doyle-Meyers LA, Roy CJ
Toxins 2015 Jun 9;7(6):2121-33

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In vivo characterization of alveolar and interstitial lung macrophages in rhesus macaques: implications for understanding lung disease in humans.

Cai Y, Sugimoto C, Arainga M, Alvarez X, Didier ES, Kuroda MJ
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2821-9

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Mitochondrial targeted peptides attenuate residual myocardial damage after reversal of experimental renovascular hypertension.

Eirin A, Williams BJ, Ebrahimi B, Zhang X, Crane JA, Lerman A, Textor SC, Lerman LO
Journal of hypertension 2014 Jan;32(1):154-65

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Renal vein cytokine release as an index of renal parenchymal inflammation in chronic experimental renal artery stenosis.

Eirin A, Zhang X, Zhu XY, Tang H, Jordan KL, Grande JP, Dietz AB, Lerman A, Textor SC, Lerman LO
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2014 Feb;29(2):274-82

Western blot

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Western Blot: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Analysis in human liver tissue.

Immunohistochemistry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining of human placenta shows moderate to strong cytoplasmic positivity in Hofbauer cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining of human lung shows moderate to strong cytoplasmic positivity in macrophages.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining of human cerebral cortex shows no cytoplasmic positivity in neuronal cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining of human liver shows moderate cytoplasmic positivity in Kupffer cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining in human lung and cerebral cortex tissues. Corresponding MRC1 RNA-seq data are presented for the same tissues.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining of human colon using Anti-MRC1 antibody.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining of human lymph node.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining of human cerebral cortex, liver, lung and placenta using Anti-MRC1 antibody NBP1-90020 (A) shows similar protein distribution across tissues to independent antibody NBP2-33439 (B).

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: MMR/CD206/Mannose Receptor Antibody [NBP1-90020] - Staining of human cerebral cortex, liver, lung and placenta using Anti-MMR/CD206/Mannose Receptor antibody NBP1-90020 (A) shows similar protein distribution across tissues to independent antibody NBP2-33439 (B).