Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN357138 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1252-1282), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 1252-1282, C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression.
The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses.
Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45.
77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic link.
Negative regulation of T cell activation by placental protein 14 is mediated by the tyrosine phosphatase receptor CD45.
Stanton T, Boxall S, Hirai K, Dawes R, Tonks S, Yasui T, Kanaoka Y, Yuldasheva N, Ishiko O, Bodmer W, Beverley PC, Tchilian EZ
Proceedings of the National Academy of Sciences of the United States of America 2003 May 13;100(10):5997-6002
Proceedings of the National Academy of Sciences of the United States of America 2003 May 13;100(10):5997-6002
The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses.
McCann FE, Vanherberghen B, Eleme K, Carlin LM, Newsam RJ, Goulding D, Davis DM
Journal of immunology (Baltimore, Md. : 1950) 2003 Mar 15;170(6):2862-70
Journal of immunology (Baltimore, Md. : 1950) 2003 Mar 15;170(6):2862-70
Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45.
Fernandis AZ, Cherla RP, Ganju RK
The Journal of biological chemistry 2003 Mar 14;278(11):9536-43
The Journal of biological chemistry 2003 Mar 14;278(11):9536-43
77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic link.
Vogel A, Strassburg CP, Manns MP
Genes and immunity 2003 Jan;4(1):79-81
Genes and immunity 2003 Jan;4(1):79-81
Negative regulation of T cell activation by placental protein 14 is mediated by the tyrosine phosphatase receptor CD45.
Rachmilewitz J, Borovsky Z, Riely GJ, Miller R, Tykocinski ML
The Journal of biological chemistry 2003 Apr 18;278(16):14059-65
The Journal of biological chemistry 2003 Apr 18;278(16):14059-65
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