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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN967867 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 535-730) antibody
- Antibody type
- Monoclonal
- Antigen
- Human CD45 (alternatively spliced)
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 69
- Vial size
- 50 µg
- Concentration
- 250 µg/ml
- Storage
- Store undiluted at -20°C.
Submitted references SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription.
Regulation of the calcium/NF-AT T cell activation pathway by the D2 domain of CD45.
Increased enzymatic activity of the T-cell antigen receptor-associated fyn protein tyrosine kinase in asymptomatic patients infected with the human immunodeficiency virus.
The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.
CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.
Wu L, Fu J, Shen SH
Molecular and cellular biology 2002 Apr;22(8):2673-86
Molecular and cellular biology 2002 Apr;22(8):2673-86
Regulation of the calcium/NF-AT T cell activation pathway by the D2 domain of CD45.
Wang Y, Liang L, Esselman WJ
Journal of immunology (Baltimore, Md. : 1950) 2000 Mar 1;164(5):2557-64
Journal of immunology (Baltimore, Md. : 1950) 2000 Mar 1;164(5):2557-64
Increased enzymatic activity of the T-cell antigen receptor-associated fyn protein tyrosine kinase in asymptomatic patients infected with the human immunodeficiency virus.
Phipps DJ, Yousefi S, Branch DR
Blood 1997 Nov 1;90(9):3603-12
Blood 1997 Nov 1;90(9):3603-12
The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.
Biffen M, McMichael-Phillips D, Larson T, Venkitaraman A, Alexander D
The EMBO journal 1994 Apr 15;13(8):1920-9
The EMBO journal 1994 Apr 15;13(8):1920-9
CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.
Sieh M, Bolen JB, Weiss A
The EMBO journal 1993 Jan;12(1):315-21
The EMBO journal 1993 Jan;12(1):315-21
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