ABIN966101

antibody from antibodies-online

Targeting: ESR1 ER-alpha, Era, ESR, NR3A1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966101

Provider

antibodies-online

Product name

anti-Estrogen Receptor 1 (ESR1) (pSer167) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine 167 (L-A-SP-T-N).

Reactivity

Human

Host

Rabbit

Epitope

pSer167

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity.

Shah YM, Rowan BG
Molecular endocrinology (Baltimore, Md.) 2005 Mar;19(3):732-48

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Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.

Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H
The Journal of biological chemistry 2001 Mar 30;276(13):9817-24

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Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.

Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV, Cheng JQ
Cancer research 2001 Aug 15;61(16):5985-91