NBP2-34720AF488
antibody from Novus Biologicals
Targeting: TYRP1
b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations [0]
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- Product number
- NBP2-34720AF488 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TYRP1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
Submitted references KLF4 inhibition promotes the expansion of keratinocyte precursors from adult human skin and of embryonic-stem-cell-derived keratinocytes.
Fortunel NO, Chadli L, Coutier J, Lemaître G, Auvré F, Domingues S, Bouissou-Cadio E, Vaigot P, Cavallero S, Deleuze JF, Roméo PH, Martin MT
Nature biomedical engineering 2019 Dec;3(12):985-997
Nature biomedical engineering 2019 Dec;3(12):985-997
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